Methods and systems for generating and processing an assessment examination answer sheet are disclosed. An answer sheet is formatted by question, column or section using a layout tool and includes calibration marks, and examinee and examination identifiers. The format is stored in a computer-readable form, such as an XML file. A conventional printer prints the answer sheet prior to a test administration. Upon completion, a scanned image of the answer sheet is produced using a conventional scanner. The calibration marks are used to determine relative positions of answer sheet elements and to determine light and dark answer values. The examinee and examination identifiers identify the examinee and the proper stored format. Automatic grading ensues. A graphical user interface ("GUI") assists grading of the answer sheet. The GUI may use confidence level indicators to denote answer choices or questions for which the grading system cannot precisely determine the intended response.