Advanced Placement Program (AP) Examinations in Macroeconomics, Microeconomics, and Comparative Government and Politics were studied to examine college course performance and gender differences. It was concluded that students who had received college credit for AP performed as well or better in higher-level college courses in Macroeconomics and Microeconomics than students who had not taken AP courses. Gender differences in performance were observed in all three examinations, but the greatest gender differences, favoring male students, were observed for Comparative Government and Politics. A survey of instructors of Comparative Government and Politics indicated that only a small percentage of instructors had observed gender differences in performance in their courses, however.