This memorandum is based on a paper prepared for the meetings of the Society for General Systems Research—AAAS, Symposium on General Systems Theory and Research in Berkeley, California on December 30, 1965. The author proposes and discusses a general theory of process as equivalent to problem solving and to a methodology of design. He points out that a methodological theory of instruction is at variance with most extant theories of learning, notes that recent developments (e.g., programmed instruction and its amplifications in computer guided instruction) have intuitively adopted much of the methodology of systems, and indicates that their further development would seem to require an explicit recognition of their systems character and an alignment of instruction theory with general systems theory.